In a new scientific review, the International Society of Sports Nutrition (ISSN) highlights astaxanthin among antioxidants being investigated for their potential to support exercise performance and recovery, with current evidence suggesting it does not appear to blunt training adaptations.
“It is an important step forward that ISSN clearly highlights astaxanthin in this category. It shows that the evidence has strengthened and that the ingredient is being increasingly recognized as a relevant complement for those looking to get more out of their training”, says Behnaz Shakersain, Scientific Affairs Manager at AstaReal.
For many years, the use of antioxidants in connection with exercise has been debated. During physical activity, the body naturally produces reactive oxygen species (ROS). Although ROS are potentially damaging at excessive levels, they also play an essential role in signaling processes that drive beneficial adaptations to training, including muscle remodeling and improved endurance capacity.
“The body requires a certain level of reactive oxygen species for normal cellular signaling and adaptation. Problems arise when oxidative stress becomes excessive and disrupts redox balance. Unlike some high-dose antioxidant supplements that may interfere with these signaling pathways, astaxanthin appears to help manage excessive free radicals while preserving the physiological signals involved in training adaptation.”
In its recent position stand, ISSN makes a clear distinction between different types of antioxidants, their effective doses and potential impact on performance, recovery and training adaptations. Astaxanthin is highlighted as an ingredient that can support recovery without interfering with exercise-induced adaptations.
“Not all antioxidants act in the same way. While more well-controlled human studies are needed for more definitive conclusions, astaxanthin appears to help maintain redox balance, allowing the body to retain the signaling needed for strength and endurance development, while helping limit excessive oxidative stress.”
In the review, ISSN highlights four antioxidants with the strongest scientific support in this area: creatine, omega-3 fatty acids, astaxanthin, and tart cherry.
“Its discussion alongside well-established compounds such as creatine and omega-3 fatty acids reflects growing scientific interest in astaxanthin as a promising antioxidant for managing exercise-related oxidative stress while preserving physiological training adaptations.”
ISSN is an international, non-profit organization that brings together researchers, clinicians, and experts in sports nutrition. The organization publishes the peer-reviewed Journal of the International Society of Sports Nutrition and develops official position stands on diet, supplementation, and performance.